Prof. Simeon I. B. CADMUS


Prof. Simeon I. B. CADMUSDr. Simeon I. B. CADMUS

DVM (Ibadan), MVPH (Ibadan), Ph.D. (Ibadan)

PROFESSOR

 

Area of Specialization:

Bacterial Zoonoses and Food Hygiene(Veterinary Public Health)Member, Nigerian Veterinary Medical Association

Member, American Society of Microbiology

Office:

Room 001, Immunology Laboratory Building Department of Veterinary Public Health and Preventive Medicine

Tel. 00 234 (0) 802 375 1093

Email: 

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Long Term Goals:

To set-up a TB Research Centre in Nigeria for the training of scientists who will be involved in providing laboratory support to hospitals and other healthcare centres. This centre will also among other things lead in the investigation of modern diagnostic tools for the diagnosis, treatment and control of TB in Nigeria as well as provide basic epidemiological data on TB in the country.

Professional Vision:

To participate in the discovery of techniques, methods and treatments that will bring about the control and eradication of tuberculosis in both humans and animals in Nigeria and the world at large.

Current Research Projects:

a) Improving Benefits of Urban and Peri-urban Production through Management of Associated Human and Environmental Health Risks in Nigeria (with emphasis on Tuberculosis) IDRC/ILRI Funded Project

b) Drug-Susceptibility studies on some strains of M. tuberculosis and M. bovis isolated from TB-Patients and Cattle in Ibadan, South-western Nigeria.

 

c) Pilot study on the incidence of Cryptosporidiosis in children in Ibadan, South  western Nigeria.

d) Determining the burden of zoonotic transmission of tuberculosis in Nigeria: A study to inform public health policy making. (John D. and Catherine T. MacArthur / University of Ibadan Re-entry Grant 2006)

e) Antituberculosis evaluation of 20 of medical plants identified from the south west Nigerian ethnomedicine (University of Ibadan Multidisciplinary Senate Research Grant 2007).

 

LIST OF PUBLICATIONS

 

My research activities have been targeted at providing valuable information and clues to promoting public health in the areas of:
 
i. Bacterial and Protozoan Zoonoses.
 
ii. Conventional/molecular epidemiology and diagnosis of tuberculosis in humans and animals.
 
iii. Epidemiology of brucellosis in humans and animals iii. Food Safety and Hygiene. These are reflected in some of the publications below:

1. Cadmus, S.I.B., S.V. Gordon, S.V., Hewinson, R.G., Smith, N.H. (2011). Exploring the use of molecular epidemiology to track bovine tuberculosis in Nigeria: An overview from 2002 to 2004. Veterinary Microbiology doi:10.1016/j.vetmic.2011.02.036. Abstract

 
2. Jenkins, A.O., Cadmus, S.I.B., Venter, E.H., Pourcel, Hauk, C.Y., Vergnaud, G., Godfroid, J. (2011). Molecular epidemiology of human and animal tuberculosis in Ibadan, Southwestern Nigeria doi:10.1016/j.vetmic.2011.02.037.
 
3. Cadmus Simeon, Veronique Hill, Dick van Soolingen, and Nalin Rastogi (2011). Spoligotype  Profile of Mycobacterium tuberculosis Complex Strains from HIV-Positive and -Negative Patients in Nigeria: a Comparative Analysis. Journal of Clinical Microbiology, 49: 220-226
 
4. Stefan Berg, M. Carmen Garcia-Pelayo, Borna Muller, Elena Hailu, Benon Asiimwe, Kristin Kremer, James Dale, M. Beatrice Boniotti, Sabrina Rodriguez, Markus Hilty, Leen Rigouts, Rebuma Firdessa, Adelina Machado, Custodia Mucavele, Bongo Nare Richard Ngandolo, Judith Bruchfeld, Lauran Boschiroli, Annelle Muller, Naima Sahraoui, Maria Pacciarini, Simeon Cadmus, Moses Joloba, Dick van Soolingen, Anita L. Michel, Berit Djnne, Alicia Aranaz, Jakob Zinsstag, Paul van Helden, Francoise Portaels, Rudovick Kazwala, Gunilla Kallenius, R. Glyn Hewinson, Abraham Aseffa, Stephen V. Gordon, and Noel H. Smith (2011). African 2, a clonal complex of Mycobacterium bovis
epidemiologically important in East Africa. Journal of Clinical, 193 (3): 670-678.
 
5.  Cadmus, SI, Okoje VN, Taiwo BO, van Soolingen D. (2010). Mycobacterium tuberculosis exposure for dentists, Ibadan, Nigeria. Journal of Emerging Infectious Diseases (DOI: 10.3201/eid1609.100447). Abstract
 
6. Cadmus, Simeon IB, Oluwasola Abideen O, Okolo Clement A, Ngwu Bethrand A F. (2010). Pattern of tuberculous lymphadenitis diagnosed by fine needle aspiration cytology at the University College Hospital, Ibadan, Nigeria. African Journal of Medicine and Medical Sciences 39: 193-197.
 
7. Cadmus, S.I.B. (2010).The transmission chain of Mycobacterium bovis from cattle to humans and within the human setting in Nigeria: facts, realities and way forward. Tropical Veterinarian 28: 1-12.
 
8. Cadmus, S.I.B., Adesokan, H.K., Adejuwon, T.A. and Adeyemi, M.O. (2010). Retrospective study ofbovine tuberculosis and other diseases of public health importance in Oko-Oba Abattoir, Lagos State. Tropical Veterinarian 28: 21-30.
 
9. Ibrahim, S., Agada, C. A., Umoh, J.U., Ajogi, I., Farouk, U.M., Cadmus, S.I.B. (2010).  Prevalence of bovine tuberculosis in Jigawa State, North-western Nigeria. Tropical Animal Health and Production 42: 133-135.
 
10. Cadmus S I B, Adesokan H K, Adedokun B O, Stack J A (2010). Seroprevalence of bovine brucellosis in trade cattle slaughtered in Ibadan, Nigeria, from 2004-2006. Journal of the South African Veterinary Association 81(1): 50-53.
 
11. Cadmus, S.I.B., Yakubu, M. K., Magaji, A. A., Jenkins, A.O. Jenkins, van Soolingen, D. (2010). Mycobacterium bovis, but also M. africanum present in raw milk of pastoral cattle in north-central Nigeria. Tropical Animal Health and Production D01: Abstract 10.1007/s11250-010-9533-2.
 
12. Ibironke, A. A., McCrindle, C.M.E., Adejuwon, T.A., Cadmus, S.I.B. (2010). Losses associated with mortality of cattle and camels during transportation to Oko-Oba Abattoir, Lagos State, Nigeria. European Journal Translational Myology - Basic Applied Myology; 1 (1&2): 13-16.
 
13. Cadmus, S.I.B., Adesokan, H.K., Okker, M., Jahans, K. (2010). Mycobacterium fortuitum from lesions of slaughtered pigs in Ibadan, Nigeria. Rev. sci. tech. Off. int. Epiz., 29 (3), 705-711. Abstract.
 
14. Cadmus, S.I. Agada, C.A., Onoja, I.I., Ibrahim, S. (2010). Risk factors associated with bovine tuberculosis in some selected herds in Nigeria. Tropical Animal Health and Production,42: 547-549.
 
15. Cadmus, S.I.B., Adesokan, H.K. (2010). Bovine fetal wastage in Southwestern Nigeria: A survey of some abattoirs. Tropical Animal Health and Production, 42: 617- 621.
 
16. Cadmus S.I., Adesokan H.K., Jenkins A.O., van Soolingen D. (2009). Mycobacterium bovis and M. tuberculosis in Goats, Nigeria. Journal of Emerging Infectious Diseases DOI: 10.3201/eid1512.090319.
 
17.18. Cadmus, S.I.B., Adesokan, H.K., Osikoya, I.E. (2009). Brucellosis in trade cattle in Lagos State: an investigation of two abattoirs. Nigeria Veterinary Journal 29 (4): 43-46.
 
18. Cadmus S.I.B. and Adesokan H.K. (2009). Causes and implications of bovine organs/offal condemnations in some abattoirs in Western Nigeria. Tropical Animal Health and Production DOI: 10.1007/s11250-009-9334-7. Abstract
 
19.Borna Mller, Markus Hilty, Stefan Berg, M. Carmen Garcia-Pelayo, James Dale, Laura Boschiroli, Simeon Cadmus, Bongo Nar Richard Ngandolo, Rudovick Kazwala, Bassirou Bonfoh, BM Njanpop-Lafourcade, Naima Sahraoui, Djamel Guetarni, Abraham Aseffa, Meseret H. Mekonnen, Voahangy Rasolofo Razanamparany, Herimanana Ramarokoto, Berit Djnne, James Oloya, A Machado, Custodia Mucavele, Eystein Skjerve, Francoise Portaels, Leen Rigouts, Anita Michel, Annlle Mller, Gunilla Kllenius, Paul D van Helden, Glyn Hewinson, Jakob Zinsstag, Stephen V. Gordon and Noel H. Smith (2009). African 1; An Epidemiologically Important Clonal Complex of Mycobacterium bovis Dominant in Mali, Nigeria, Cameroon and Chad. Journal of Bacteriology 191 (6): 1951-1960. Abstract
 
20. Cadmus, S.I.B., Jenkins, A.O., Godfroid, J., Osinusi, K., Adewole, I.F., Murphy, R.L., Taiwo, B.O. (2009) Mycobacterium tuberculosis and Mycobacterium africanum in Stools from Children in an Immunization Clinic in Ibadan, Nigeria. International Journal of Infectious Disease 13: 740-744. Abstract
 
21. Cadmus, S.I.B., Adesokan, H.K. and Stack, J.A. (2008). Co-Infection of brucellosis and tuberculosis in slaughtered cattle In Ibadan, Nigeria: a case report. Veterinaria Italiana 44 (3): 557-558.
 
22. Cadmus, S.I.B., Adesokan, H.K., Adepoju, A.F. and Otesile, E.B. (2008).Zoonotic risks and transmission of Mycobacteria species from cows milk and slaughtered cattle to man in Ibadan: role of butchers. Nigerian Veterinary Journal 29 (1): 30-39.
 
23. Cadmus, S.I.B., Adesokan, H.K., Stack, J. (2008). The use of the milk ring test and rose bengal test in brucellosis control and eradication in Nigeria. Journal of the South African Veterinary Association 79 (3): 113-115. Abstract
 
24. Cadmus, S.I.B., Adesokan, H.K. and Awosanya, A.E.J. (2008). Public health issues and observations made during meat inspection at Bodija Municipal Abattoir, Ibadan, Oyo state, Nigeria. Nigerian Veterinary Journal 29 (2): 43-47.
 
25. Cadmus, S.I.B. and Adesokan, H.K. (2007). Phenotypic characterization and spoligotype profiles of Mycobacterium bovis isolated from unpasteurized cow milk in Ibadan, Nigeria. Tropical Veterinarian 25 (2): 65-72.
 
26. Cadmus, S.I.B., Alonge, D.O. and Adesokan, H.K. (2007). Meat inspection and cultural isolation of Mycobacteria as predictors of bovine tuberculosis in Ibadan, Nigeria. Tropical Veterinarian 25 (3): 101-105.
 
27. Cadmus, S., Palmer, S., Okker M., Dale, J.; Gover, K., Smith, N., Jahans, K., Hewinson, R.G. and Gordon, S.V. (2006). Molecular analysis of human and bovine tubercle bacilli from a local setting in Nigeria. Journal of Clinical Microbiology. 44 (1): 29-34. Abstract
 
28. Cadmus S.I.B, Ijagbone I.F., Oputa H.E., Adesokan H.K. and Stack J.A. (2006). Serological survey of brucellosis in livestock animals and workers in Ibadan, Nigeria. African Journal of Biomedical Research, 9: 163-168.
 
29. Zinsstag, J., Kazwala, R.R., Cadmus, I. and Ayanwale. L. (2006). Mycobacterium bovis in Africa, Mycobacterium bovis infection in Animals and Humans. C.O. Thoen, J.H. Steele and M.J. Gilsdorf. Publ. Blackwell, 2nd ed. 199-210.
 
30. Cadmus, S.I.B. and Arinola, O.G. (2005). Reduced plasma levels of essential trace elements in Mycobacterium bovis infected cattle in Nigeria. European Journal of Scientific Research, 6: 58-59.
 
31. Kehinde, A.O. Obaseki, F.A. and Cadmus, S.I. andBakare, R.A. (2005). Diagnosis of tuberculosis: urgent need to strengthen laboratory services. Journal of the National Medical Association, 97 (3): 394 - 396.
 
32. Cadmus, S., Oluwasola, O.A. and Gordon, S. (2005). Molecular methods for the accurate assessment of Mycobacterium bovis infection. International Journal of Tuberculosis and Lung Diseases. 9 (6): 705.
 
33. Cadmus, S. I. B. and Arinola, O.G. (2005). Evaluation of the 48 hour, 72 hour and 96 hour readings of tuberculin test for the screening of tuberculosis in cattle. African Journal of Clinical and Experimental Microbiology, 6 (3): 223-226.
 
34. Cadmus, S.I.B.; Atsanda, A.A.; Oni, S.O. and Akang, E.E.U. (2004). Bovine tuberculosis in one cattle herd in Ibadan in Nigeria. Veterinary Medicine Czech, 49 (11): 406 - 412.
 
35. Oyedele, O.I., Oluwayelu, D.O., Cadmus, S.I.B., Odemuyiwa, S.O. and Adu, F.D. (2004). Protective levels of canine distemper virus antibody in an urban dog population using plaque reduction neutralization test. Onderstepoort Journal of Veterinary Research, 17: 227-230.
 
36. Cadmus, S.I.B. (2003). Tuberculosis in food animals. Nigerian Veterinary Journal, 24 (3): 72-75.
 
37. Nottidge H.O. Ajadi, R.A., Cadmus, S.I.B., Shonibare, O., Okewole, E.A.,Taiwo, V.O., Emipke, B., Adedokun, R.A. and Oduye, O.O. (2003). Liver cirrhosis associated with a non-responsive ascites in a 10-month-old Alsatian dog a case report. African Journal of Biomedical Research, Vol. 6 (3): 151-153
 
38. Oduye,O.O., Antia, R.E., Nottidge, H.O., Taiwo, V.O., Adeyemi, I.G., Okewole, E.A., Adeyemo, O.K., Cadmus, S.I.B., Sonibare, A.O., Ajadi, R.A. and Lasisi, O.T. (2001). Trypanosomiasis in city dogs in South-western Nigeria. Tropical Veterinarian, 19 (2): 49-54.
 
39. Cadmus, S.I.B. (2001). The zoonotic implications of bovine tuberculosis in animals and humans in Nigeria. Proceedings of the International Conference on Food Safety and Security in Ibadan, Nigeria Held August 1ST -3RD 2001 pg 99-105.
 
40. Cadmus, S.I.B., Olugasa, B.O., Ogundipe, G.A.T. (1999). The prevalence and zoonotic importance of bovine tuberculosis in Ibadan. Being the text of a paper presented at the 36TH Annual Conference of the Nigerian Veterinary Medical Association held in Kaduna, 25TH -31ST October 1999.

Foreign Training:

1. 2006- Short-term Training in Molecular Tools and Epidemiology of Tuberculosis, Institut Pasteur, Paris

2. Johns Hopkins School of Public Health (Dr. Ying Zhang Laboratory)

Studies on Drug Susceptibility in Multi-Drug Resistance Strains of TB.

3. University of Pennsylvania, Department of Infectious Disease (Prof. Rubin Harvey's Laboratory. 2-weeks Laboratory Training in Biochemical Dynamics of Tuberculosis.

 

4. (Veterinary Laboratories Agency, United Kingdom) from January 28th March 31st 2004 on:

 

i. Processing of bovine tissues for TB diagnosis.

 

ii. Molecular typing of M. bovis.

 

iii. Techniques of ruminant immunology relevant to the assessment of immune responses in cattle infected with bovine TB.